I post process with Photoshop and the primary mechanism for adjusting contrast is Curves. Unless you clip highlight or shadow tonalities in scanning or in making a curves adjustment you should not love any tonal values in making the curves adjustment. I also have not seen any problem with increased grain when adjusting curves, though I guess it is possible depending on what you start with and how abrupt your adjustment is. The main danger is making curve corrections is that if the correction is to drastic it may cause posterization, but this is pretty easy to see on the screen.
But primarily you just make sure to avoid clipping tonal values at both ends in making adjustments for contrast. Never use the Brightness/Contrast tool in Photoshop as this will nearly always clip tonal values.
Sandy
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