Brian,

You might be able to get to the Wawona Grove of Giant Sequoias that time of year. You will be able to drive up to the Badger Pass Ski Resort provided you have chains or four wheel drive. The closest places to stay are in Fish Camp. Other than those possibilities you're going to be stuck in Yosemite Valley because of closed roads in the high country.

The drive from Fish Camp to Yosemite Valley on Highway 41 is gorgeous, and full of excellent photo opportunities. My favorite spot at sunset is at the burn area just before you start dropping altitude. You'll see it, and there is a convenient turnoff with plenty of room to park.

Late April/early May is an excellent time of year in Yosemite Valley. The waterfalls will be at full flow, and there will probably dogwoods blooming along the river. But if you want something different, why not skip Yosemite and go to King's Canyon instead?