Since Skyline Drive and the Blue Ridge Parkway will be in your back yard...

http://www.amazon.com/Best-Blue-Ridg...7499388&sr=1-1

I'd suggest the Skyline, the BRP, and nearby areas as your primary "hunting grounds" as they will be accessible on weekends, especially long ones.

If you want to travel by air, you can get just about anywhere from DC including the famous locations in the Western US.

Cheers, Steve