Get a medium format camera. I'd go for a Mamiya RZII set up.
Let me tell you why you should go MF instead of LF. Firstly, you might be mislead a bit about the advantage of the large ground glass. Yes, it is big but it is also upside down and can be somewhat dim at times as the maximum aperture of most LF lenses is not that large. And then there's the fact that, once you have all your settings in place, you have to tell the subject to hold still while you close down the lens, cock the shutter, slide in the film holder, remove the darkslide and make the exposure.
An MF camera such as an RZ in comparison is much easier to use. You have a large sized ground glass you can look at with both eyes, the image is right side up and, since it's an SLR, you can capture spontaneous expressions much more easily. That, and you can shoot more frames than you could with LF for the same price.
Don't get me wrong, I love LF portraiture but for someone coming from 35mm digital I think it would be wise to first go with MF. It's still a somewhat slower, more contemplative process than 35mm but not as extreme as LF.
Now as for quality, I really think there's no need to go 4x5 or 8x10 just because you want to print big. For years people have shot billboard campaigns on 6x7 film with no problem. And that was before there were such fine grained films like Kodak Portra 400/160 or Ektar 100.
As for your 'vision' and your project, I'd advise you to take things slowly. One thing you have to understand is that when you start using a new format and equipment it takes time to adapt and perfect your vision in that medium. You might want to first try out a few things and make sure you're really comfortable with your chosen format before you start with your project and, more importantly, before you spend lots of money.
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