I carry my 4x5 wooden folder and four lenses plus loaded filmholders, meter and filters in a rolling carry-on when flying around Europe. I let everything go through the scanner. I've had to unpack to show my equipment and have had to run the camera through separately a time or two (something about not being able to see through it...). Sometimes the film gets up to 8 scans (rarely, but sometimes when I take the same unexposed holders on multiple trips). I've had no problems with x-ray damage whatsoever.
Same goes when I'm flying inside the United States, although there I usually prefer road trips.
However, when I fly back and forth between my "home bases" in Europe and the U.S., I found that lugging so much stuff around on long-haul flights was a real pain. I now keep separate camera(s) meters and common lenses in duplicate, one set on each continent; same for tripods. I just carry the few lenses and filters I need. I'm now down to carrying 12 filters (which go fine in bubble wrap in the checked baggage) a 90mm SA and my Fuji A 240mm. If I find a good deal on either of these in the future, I'll station one of them in Europe and one in the U.S. as well. This time I'm carrying an extra meter back and forth, which I used to check the accuracy of my European meter. Usually it stays in the U.S. too.
I do return to Europe with supplies from the U.S.; boxes of 4x5 film and some dry chemistry (both just for economy, since I can get everything in Europe, just at double the price). I carry the film in the carry-on, let it go through the scanner and have had zero problems (usually one to two scans to get film from the U.S. to Vienna). Chemistry goes in the checked bags. Both film and chemistry are always in factory sealed packages. I was a little concerned that the TSA might confiscate my sodium metaborate and my PMK kits, but so far, no problems.
Hope my experiences help somewhat.
Best,
Doremus Scudder
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