Yes, if you've done everything else and you're still getting a density difference between your screen and your printer, then you would look at how well your ambient light is matching your monitor's calibration settings.

A good, basic way to start without getting too technical is something we call "the white paper test." Open up a blank, white document in Photoshop, and then hold up a sheet of your printing paper. Does it match? If the white of your paper is a lot darker than the white on your screen, then it stands to reason that your prints will appear darker when printed.

To fix this either the lighting you are using for viewing your prints needs to be increased, or the display calibration needs to be adjusted to have a lower luminosity.

-Pat Herold
CHROMiX Tech Support