Hi Peter,
Setting up isn't a problem... one can use his view camera and mount the lightbox on the extension rail of it... Focusing is no problem either if one uses LV... With Sinarback 54H & view camera, LV is really easy if one adds Sinar's LC shutter. He can then use a macro lens and stitching becomes a piece of cake by just shift the lens and the image area around the negative... The thing is that (as I said before) its got to be a multishot back, you won't gain much (if any) by using a single shot back... A multishot MFDB though, will make a night to day difference one has to try it as to believe it.
Sinar (who only makes multishot backs the later years) even came up with a set up dedicated for the job http://www.sinar.ch/en/category/products/cameras/repro/ so that museums can digitize their old films of paintings without need to redo them in digital... But it won't make a difference if one uses his own camera and lens and an older multishot MFDB instead... Its really difficult to describe with words how impressive the results can be if one uses a multishot back... The back being multishot, is the key factor.
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