Quote Originally Posted by fishbulb View Post
I have a bunch of negatives in my scanning queue; I'm going to pick a few to do four 90 degree rotation scans and see what the results are. The rotation may be enough to capture real additional data, regardless of how many pixels are actually moved.
Unless can rotate your negative exactly (and I mean exactly) 90 degrees each time, you will have to rotate something other than 90 degrees in Photoshop to get all the pixels to line up exactly. This will cause interpolation to occur, when you rotate the images, which will nullify any benefits that you hope to achieve.