I have a Microtek Artixscan M1 and recommend you stick with your V750. The F2/M2 is an upgraded faster version of the the M1, but essentially the same scanner. The big advantages if the Microtek are autofocus and the 4x5 glassless carriers. The autofocus works, but slows down the scanning process. I think this has been improved with the F2/M2. The glassless carriers are great when they work, but they're finicky as far as getting the film to seat properly. For 8x10 film, you really need to wet mount because there is no glassless carrier. The quality of these prosumer flatbeds is maxed out for now, so I don't see that a switch would help as far as quality or usability.
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