Just did a few pics of friends in a park this weekend with a 4x5. Overcast day. Was using Fomapan 100. Aperture was generally f/22, and had no problem with shutter speeds between 1/8s and 1/2s.
As Bernice mentioned, with large format portrait, you have to instruct your sitters much more. You have to tell them in advance that you're going to ask them to be very still for a short while, and tell them again just as you're finishing your focus. For a normal adult, being very still for two or three seconds is no problem, especially if they understand why.
Most important, I realized the hard way, is to keep talking to them between the moment you've finished the focus and the moment you press the shutter, or have them think or focus on something specific. I had one sitter who was easily distracted by the other members of the group and I had to redo the focus a couple of times (once after I had just put in the film holder).
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