I use lower-class Beseler 45 MXII and CB7 enlargers and have never had a problem. I started using EKTAR 25 in 35mm when it first came out -- for two reasons. I had been doing the Kodachrome 25/Cibachrome thing -- with great results -- but you know what happened with that!
I also made the switch to Ektar 25 because my main film was AGFAPAN 25 -- which made switching from B&W to COLOR a breeze.

Before EKTAR 100 in 4x5, I had been using AGFACOLOR 100 & 125, but when I made the move to EKTAR 100 4x5, I did not see any significant change in color -- or anything else.

I still miss the results from Kodachrome 25, but 100 in 4x5 is good enough!!!