Most Seneca whole plate cameras I see are plate cameras rather than film cameras. So the ground glass is situated for the thickness of glass plates in the holders rather than film. This is something that can be compensated for with shimming the ground glass. Eastman holders should fit, but I'm not 100% certain.
Whole Plate is smaller than 8x10, it's not gonna take an 8x10 back. If you want to shoot 8x10 & WP with the same camera (which I do), find an 8x10 camera and a WP reduction back.
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