1. Retrofocus design (SLR, due to mirror constraint) vs. non-retro ~symmetrical design (RF / LF) PS: they do have fall-off that is corrected by stopping down, due to mechanical vignetting, just like LF lenses but there's still the inherent fall-off from traditional designs that isn't corrected.
2. As mentioned above, designs vary, and also consider that image circle may affect this (if you are closer to the edge of the IC, more fall-off).
3. Less dynamic range available - 2 stops underexposed means you are dangerously close to just having nothing usable on the film.
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