I just updated to Maverick (OSX 10.9) and my Epson Scan does not work with the new OS.
Apple directs you to Epson, Epson directs you to Apple, but neither have the updated driver.
Epson has no definite date for the release of the updated driver, either.
I know I can use VueScan, but I prefer Epson Scan; if you do as well, don't upgrade to 10.9 until a new Epson driver is in place.
Bookmarks