After moving up from 35mm to 6x6 to 4x5, when the time came to go larger, I went straightaway to 11x14. In retrospect, I'm glad I had the sense to skip 8x10 since a contact print at in that size is nice, but I would have eventually wanted something larger. You can always print only smaller part of a larger negative or get a reducing back if you want to save some cash on film, but printing 11x14 of an 8x10 negative is quite a bit more difficult. Yes, the camera is larger, but I wheel my 11x14 camera around, and I doubt I would have carried an 8x10 very far without a similar apparatus.
It's definitely a different beast than 4x5, but once you get to 8x10, I don't think the technical problems get much different as you go even larger, the biggest problem being very long exposures; I often have to account for reciprocity in the middle of the day.
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