Evan, you didn't mention how much experience you have making prints in general? If you are new to it I would start with prints anywhere near that large.
One thing to note (I have done a ton of very large b&w prints over the years). Every method I tried was pretty messy and required-not just a dark room-but a very large dark room with ventilation and floors that wouldn't matter if they stained and could be wet mopped..
Also think about how you are going to dry them?
To be completely honest? I personally wouldn't think about doing it myself now any method but printing digitally. It solves sooooo many problems related to making big prints like negs poping from the heat of looong exposures, handling problems, drying problems, etc. etc. I wish I had a dollar per square foot for every print I trashed just because they were out of focus from the negative popping or had handling marks. If I had to do it traditionally I would send it to a lab who does it professionally.