I did a lot of product photography with an old axis-tilt Calumet 4x5 and Cambo 8x10. The clients liked to have every part of each product in focus. Tilts, swings, rise or falls and every possible adjustment - many times extreme - was sometimes required to meet that standard. When I got a base-tilt Arca Swiss focus was easier to maintain. That's really about it. For landscape and most portraits it's pretty much a non issue.