I can't see a damn thing while driving. Relationships between near-far, shapes the light is forming, etc are just about impossible for me to see while driving. I can find subjects while driving -- but not images. I prefer to walk to find the light.
No time-of-day limitations for me -- as long as there is light, one can photograph. Under the redwoods I prefer 10am to 2pm (a little later if it is not winter).