E6 and C41 is really easy in a Jobo. I use a jobo atl 2300 and Kodak Flexicolor chemistry.
C41 is a bit more forgiving then E6. You can correct for minor errors in printing or scanning.
I like the Kodak chemistry because you can buy it in large quantities, they are always consistent, last a pretty long time and its not a Blix, separate Dev, Bleach and Fixer.
In the cubes your cost per ml drops significantly, just a thought if you do a lot.