Just be honest with your description and have a policy of no refunds. I actually stated for a long time in my auctions that "if you are a pain to deal with or if you are going to have remorse please don't bid....." but got an email from ebay stating that I could not use any language in my conditions that discouraged bidding! Whatever.
If I am going to sell something I typically weigh the value of the item versus how much of a pain it is to put something on ebay. I only use ebay if it will bring significantly more. I prefer to sell things through forums but sometimes with odd items there is no choice but to go with evilbay.