4x5 really isn't that unusual in a lot of commercial fashion and beauty photography. People like Arthur Elgort and Steven Meisel and Paolo Roversi all use 4x5 and 8x10 all the time.
Jock Sturges' work is probably gong to show you the biggest differences between shooting large format and medium format.
And the classics -- Edward Weston, Wynn Bullock, and a slew of Californian bohemians. Not to mention thousands of gay bodybuilding images.
A lot of the rationale for shooting large format "people" naked or clothed, isn't (only) about the image quality so much as the experience of shooting -- people respond differently to different cameras and the required pace of shooting.
Sanders McNew (Google) mixs 5x7 with 120 for his portraits, you can see a comparison with his work.
Then of course there is the whole school of people shooting vintage portrait lenses and limiting the depth of field to a narrow section by shooting wide open and/or tilting the lens.... large format does that better.
My work really isn't "nudes". There are a few drunk girls with their clothes off or some such nonsense, but I don't go out to shoot capital N "Nudes" on purpose very often. My friends are naked sometimes, but nude is too fancy a word and I don't like the connotation ;-)
But if you just want some naked chick to slouch over a tree in some misty artsty-fartsy pose then large format is the way to go!