Someone can correct me if I'm wrong, but I believe the recommended amount of room air changes/hour is at least 10, and up to 20 for a smaller room. Figure out your cubic footage & Make sure your fan has the capacity you need-with an adequate fan and intake you simply shouldnt have odor problems, assuming that the chemicals are BETWEEN you and the exhaust, which it sounds like they are. I dont know that a purifier wouldnt work, but I think a good exhaust fan is a better idea. If the purifier is recycling room air rather than venting it OUT, then you might not have enough fresh air coming in the intake vents