A bit late to this, but... Andy is exactly right, David. For anything important/serious you want to start with a raw, FFF scan. That pulls in everything the scanner is able to extract. From that point it's just a matter of using FlexColor and Photoshop to tweak things to your liking.

I'm on an X1 rather than an X5. I also have a Coolscan LS-9000 and agree with the comment that it is a very, very good scanner. However, it is not as good as the Flextight.